Publisher: Elsevier
The ability of Aureobasidium pullulans NCYC 4012 to produce gluconic acid (GA) was firstly studied in flask batch cultures and it was found that GA productivity was not affected by initial glucose concentration, but highest substrate uptake rate was observed at glucose concentration of 80g∙L-1. The effect of oxygen mass transfer, varied by changing agitation and aeration rates or total air pressure, was evaluated in batch cultures of A. pullulans in stirred tank bioreactors. Higher productivities were attained in conditions of high oxygen mass transfer and it was proven that the use of increas ...