Publications in International Journals / Series (Article (International))
Microalgae extracts reduce appetite in zebrafish larvae linked to long-chain fatty acids and 5′-methylthioadenosine
- Moxó, Javier Sanz; Fonseca, Ana Catarina; Matos, Gabriela; Saraiva, Jorge; Pereira, Ricardo N.; Rocha, Cristina M.R.; Vasconcelos, Vítor; Urbatzka, Ralph
- Algal Research, 88(104003), 2025
Abstract
Appetite modulation is a promising strategy for obesity treatment. The presented research screened 103 microalgae extracts from three strains of microalgae (Chlorella sp., Chlorococcum sp. and Nannochloropsis oceanica) for appetite reducing activity, using high pressure processing and moderate electric fields. Two different feeding assays with zebrafish larvae were applied using either fluorescent labeled liposomes or paramecia. Two extracts of Chlorococcum sp., reduced food uptake for >30 % in the liposomes assay, while three extracts of Chlorella sp. (grown under autotrophic and heterotrophi ...
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